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Ausgabe 3/2005

Erscheinungsdatum: 08.09.2005

EDITORIAL

Good Night

A. Seidinger

Seite 01

EVENTS

Drug Discovery: From Targets to Candidates

SBS Annual Conference in Geneva, Switzerland

Seite 05

BUSINESS

Strategic Analysis of the Therapeutic Peptides Market in Europe

Frost & Sullivan

Seite 010

Business Opportunities in China

W. Yifeng, China Pharmaceutical University, Nanjing, CN

Seite 015

INTERVIEW

Research for the Health of Man and the Environment

E.-G. Afting, GSF, Munich, D

Seite 020

HTS

Academe and High Throughput Screening

J. Cechetto, McMaster University, Toronto, CAN

Seite 025

A Clear View of Discovery

White Carbon

Seite 030

Polymer Microfluidics

N. Gottschlich, Greiner Bio One, D

Seite 040

SCREENING TECHNOLOGY

Dielectrophoresis as a Screening Tool

Label-free Electrophysiology Assays

K. F. Hoettges, University of Surrey, Guildford, UK

Seite 045

CELL BASED SCREENING

Live-Cell-Imaging

S. Prechtl, Schering

Seite 050

Cell Based Assays for Ultra Highthroughput Screening

B. Kalthof, Bayer Healthcare

Seite 055

BIOMOLECULAR SCREENING

A Cell-based Screen for Modifiers of TGF-b Signaling Using a Novel Assay

J. Dennis, Mount Sinai Hospital, Toronto, CAN

Seite 060

ADME

In Vitro ADME Screening in Support of Lead Generation and Lead Optimization: Current Trends and Future Prospects

D. Kassel, Takeda, San Diego, USA

Seite 065

From Early Drug Discovery to Clinical Trails

Physiology-based Pharmacokinetic Modelling

J. Nöller, Nimbus, D

Seite 070

LeadStream - A Solution for Faster ADMETox Profiling

H. Haas, Thermo Electron

Seite 075

PROTEOMICS

Simultaneous Determination of Protein Structure and Dynamics

M. Vendruscolo, University of Cambridge, UK

Seite 080

Protein Aggregation and Fibrillation

Problems and Prospects

D. Otzen, Aalborg University, DK

Seite 085

50 Ways to Get Your Protein

Multiparallel Screening of Optimal Gene Expression Strategies

N. Mertens, VIB - Flanders Institute of Biotechnology, Ghent, B

Seite 090

VIRTUAL SCREENING

Virtual Navigation in Protein Space

D. Rognan, Institut Gilbert Laustriat, Illkirch, F

Seite 095