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Ausgabe 03/2006

Erscheinungsdatum: 04.09.2006

EDITORIAL

Exciting Times

Dr. J. van Empel

Seite 01

FOCUS ON SBS

2006 Conference Highlights

Seite 07

Enhancing the Efficiency of HTS

Testing Compound Mixtures

U. Warrior, Ph D, D.J. Burns, Abbott Laboratories, USA

Seite 08

BUSINESS

Nanopharmaceuticals

Regulatory Aspects and Safety Issues

Dr. David Rickerby, European Commission, IT

Seite 010

HIGH THROUGHPUT SCREENING

Quantitative HTS

A New Screening Platform for Lead Discovery

W. Zheng, PhD, NIH Chemical Genomics Center, USA

Seite 014

EVENTS

Assays and Cellular Targets

Conference in Las Vegas

Seite 016

PHARMACEUTICAL DEVELOPMENT

Optimizing Protein Formulations

Proteins vs. Small Molecules?

S.W.H. Martin, PhD, Pfizer Global R&D, USA

Seite 018

SCREENING

Immunotherapeutics

Peptides as Screening Tools for Epitopes

Dr. A. Beck et al., Centre d’Immunologie Pierre Fabre, FR

Seite 022

DRUG DISCOVERY

Protease-activated Receptor 2

Opportunities for Anti-inflammatory Drug Discovery

Prof. A.L. Harvey, University of Strathclyde, UK

Seite 026

EVENTS

Debut in Europe

High-Content Analysis Europe in Vienna

Seite 027

CELL BASED SCREENING

High Content Screening

Challenges and Opportunities

W.P. Bowen, PhD, TTP LabTech, UK

Seite 028

GPCRs

GPCR Heterodimers

Finding Ligands

Dr. F.H. Marshall, University of Cambridge, UK

Seite 030

PROCESS ANALYTICAL TECHNOLOGY

Screening for Excipients

Probing Polymorphic Phase Transformations by Raman Spectroscopy

Prof. T. Rades et al., University of Otago, NZ

Seite 033

CLINICALS

Counter-diffusion Capillary Crystallization for structural genomics

Prof. J.D. Ng, University of Alabama, USA; Prof. J.M. Garcia-Ruiz, Laboratorio de Estudios Cristalográficos, ES

Seite 036

SYSTEMS BIOLOGY

Systems Biology and Drug Discovery

A New Path in Genome Research

Dipl.-Biol. C. Wierling, Dr. R. Herwig, Max Planck Institute for Molecular Genetics, DE

Seite 039