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Ausgabe 02/2007

Erscheinungsdatum: 08.04.2007

EDITORIAL

Drug Discovery Technologies

A. Kolb, PhD, Key Tech Solutions, USA

Seite 01

INTERVIEW

European Drug Discovery

10th Anniversary of MipTec

D. France, ArQule, USA

Seite 08

EXPERT OPINION

Compound Screening Collections

C.A. Lipinski, PhD, Melior Discovery, USA

Seite 010

Accuracy and Precision as Strategic Concerns

W.P. Janzen, Amphora Discovery, USA

Seite 012

BUSINESS

Operational Excellence at API Sites

Differences in Performance

T. Friedli et al., University of St. Gallen, Switzerland

Seite 014

CELL BASED ASSAYS

Use of Frozen Cells in Drug Discovery

Uncoupling Cell Culturing from Cell-Based Screening

Dr. G.J.R. Zaman, Organon, The Netherlands

Seite 018

CELL BASED SCREENING

Application of Microplate Cytometry

Assay Development for HT High Content Screening

D. Auld, PhD, et al., NIH Chemical Genomics Centre, USA

Seite 022

DRUG DISCOVERY

In-silico Cell Electrophysiology

A Step Closer to High Throughput Drug Screening

A. ul Haque, D. M. Porterfield, Purdue University, USA

Seite 024

COMPANY PROFILE

Research and Innovation in Assay Development

Cisbio international, France

Seite 026

SCREENING

Synthetic Mutant Libraries

Powerful Tool to Develop of Novel Enzymes

Dr. K. Wellesen, Dr. T. Waldmann, Operon Biotechnologies, Germany

Seite 027

EVENTS

High Content Analysis

Seite 029

PROTEIN-PROTEIN INTERACTIONS

Discovery of HIV-1 Fusion Inhibitors

Targeting the Zipper of the HIV-1 Spike

G. Dams, MS; K. van Acker, PhD; Tibotec, Belgium

Seite 030

PROTEIN ANALYSIS

GMP Conform Protein Analysis

New Analytical Solutions

Dr. A. Wattenberg, Dr. K. Aschermann, Protagen, Germany

Seite 032

CLINICALS

Sound, Science And Cystals

Improved Crystallization and Particle Engineering

G. Ruecroft, Prosonix, UK

Seite 034

FOOD ANALYSIS

Computational Chemistry in Food Science

Predicting the Structure and Properties of Food Molecules

Dr. W.L. Kerr, University of Georgia, USA

Seite 037

IMAGING

Applications of PET for Molecular Imaging in Cancer

Dr. A. McMahon, University of Manchester, UK

Seite 040