Archiv SCREENING

Linné’s System of Nature

Prof. F. Wuketits, University of Vienna, Austria

Seite 01

The Drug Discovery Process in Academics

Opportunity Knocks

M. Glicksman, PhD, Brigham and Women’s Hospital, USA

Seite 08

Ernst & Young’s 2007 Biotechnology Reports

Dr. J. Schüler, Ernst & Young, Germany

Seite 010

Molecular Biodiscovery in the Maurice Wilkins Centre

A Multidisciplinary Platform

R.J. Ramsay, Prof. E.N. Baker, The University of Auckland, New Zealand

Seite 012

Fluorescent versus Luminescent Reporters in HTS

Opportunities yet Untapped

N.M. Gorenstein, L.V. Avramova, Purdue University, USA

Seite 017

Advanced Light Microscopy Methods:

Live Cell Imaging and High Content Screening

Dr. T. Zimmermann, Centre for Genomic Regulation (CRG), Spain

Seite 020

High-content Assays Have Come a Long Way

Their Use within Drug Discovery

Dr. A. Scheel, Evotec, Germany

Seite 024

Advanced Electron Microscopy in Life Sciences

Finding the Place of Interest

Dr. B.M. Humbel et al., Utrecht University, The Netherlands

Seite 026

Nutritional Metabonomics

Deciphering Nutrition Effects through Metabolic Profiling

S. Rezzi, PhD et al., Nestlé Research Center, Switzerland

Seite 028

Patch Clamping hERG

Validation of an Automated Assay for Safety Studies

Dr. G. Rast et al., Altana Pharma, Germany

Seite 030

Evolution of Drug-metabolizing CYP Genes

Phylogenetic Reflections of the Vertebrate CYP1-3 Gene Families

M.C. Celander, PhD, Göteborg University, Sweden; Woods Hole Oceanographic Institution, USA

Seite 034

Limitations in P450 Inhibition Data in Drug Discovery

B.M Amore, PhD, L.C Wienkers, PhD, Amgen, USA

Seite 036