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Ausgabe 2/2008

Diese Ausgabe als ePaper lesen.

Erscheinungsdatum: 27.03.2008

EDITORIAL

Drug Discovery

Changing Gears? Not So Fast, Please

R. Macarron, President of the Society for Biomolecular Sciences

Seite 01

EVENTS

Label-free Technologies in Drug Discovery

SBS Symposium in Dresden

Seite 08

Polymorphism & Patenting

Seite 08

BUSINESS

Reincarnation In Biotech

Is There Life After Death?

M. Brännback et al., Åbo Akademi University, Finland

Seite 010

ASSAY TECHNOLOGY

Antibody Microarray-based Screening

Label-dependent vs. Label-free Detection

C. Wingren et al., Lund University, Sweden

Seite 012

Kinase Assay Development

A Strategy for Comprehensive Kinase Profiling for Drug Discovery

M. Gouda, Carna Biosciences, Japan

Seite 015

IMMUNOTHERAPEUTICS

Therapeutic Antibodies

Structure Assessment by Mass Spectrometry from Screening to Clinical Batches

A. Beck et al., Centre d’Immunologie Pierre Fabre (CIPF), France

Seite 018

SYSTEMS BIOLOGY

The Grand Challenge for European Biology

Part II: Networks for Life

H. V. Westerhoff, Manchester Interdisciplinary Biocentre, United Kingdom

Seite 022

DATA MANAGEMENT

A View on Screening Platforms

Antibody Screening Gets Extreme Makeover

K.J. Morrow Jr., Newport Biotech Consultants, USA

Seite 024

CLINICALS

Biotechnology-derived Therapeutics

Immunogenicity – the Regulatory Point of View

E.-M. Jahn et al., Paul-Ehrlich-Institut, Langen Germany

Seite 028

PLASMA MEDICINE

Physical Plasma

Its Possible Use in Medicine

U. Lindequist et al., University of Greifswald, Germany

Seite 032

INTERVIEW

A New Generation of Discovery

Applied Biosystems' SOLiD System

M. Rhodes, Applied Biosystems, USA

Seite 034

COMPANY PROFILE

Transport Proteins the Final Frontier?

From Clamping to Surfing in No Time

IonGate Biosciences, Germany

Seite 036

APPLICATION NOTES

Rapid, Fail-early Screening

Streamlining Drug Discovery

Genetix, United Kingdom

Seite 038

New Reproter Gene Technology

Monitoring Transfection Using Luciferase Reporter Assays

M. Stosik et al., amaxa, Germany

Seite 040

CELL BASED SCREENING

Mechanisms Of Metastasis

Cellix’s VenaFlux Platform Pursues Metastatic Movement

K. Fitzgerald et al., Cellix, Ireland

Seite 042

Non Binding Surfaces

A New Technology for Assay Development and HTS

R. Heller, Greiner Bio-One, Germany

Seite 044