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Ausgabe 3/2008

Diese Ausgabe als ePaper lesen.

Erscheinungsdatum: 09.07.2008

EDITORIAL

“High-Definition” FRET/FLIM

Screening Is Believing

F.S. Wouters, University Medicine Goettingen, Germany

Seite 01

EVENTS

Biotechnica 2008

More to Offer Than Ever Before

Seite 08

Compound Libraries 2008

Design – Synthesis – Hit-to-lead Optimisation

Seite 09

INTERVIEW

Surfing on the Calcium Waves to Understand Heart Rhythm

J. Lytton, University of Calgary, Canada

Seite 010

RNAi TECHNOLOGY

Automated Gene Silencing

High-throughput Transfection for Genome-wide siRNA Screens

K. Korn, Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), Germany

Seite 012

HIGH CONTENT SCREENING

FLIM for High Content Screening

Thinking Outside of the Box

T.J. Collins, McMaster University; D.W. Andrews, Canada Research Chair in Membrane Biogenesis, Canada

Seite 014

TARGETS

Targeting Protein/Protein Interactions

Protein Kinase CK2 as a Prime Example for a Novel Concept

K. Niefind, University of Cologne, Germany; O.-G. Issinger, University of Southern Denmark

Seite 018

CELL BASED ASSAYS

Drug Discovery Automation

Development of Cardiac Cell Based Assays to Study Drug Efficacy and Toxicity

A. Davies et al., Trinity College Dublin, Republic of Ireland

Seite 021

DRUG DISCOVERY

Drug Repositioning by Cellular Profiling

Serendipity by Design

A. Brinker, J.S. Caldwell, Novartis Research Foundation (GNF), USA

Seite 026

BUSINESS

Medical Biotechnology in Germany 2008

An Economic Overview

S. Sydow, S. Throm, VFA Bio, Germany

Seite 030

APPLICATION NOTES

Automated Nanoliter Pipetting

Simplifying Protein Crystallography Set-up

J. Jenkins, TTP LabTech, United Kingdom

Seite 034

Cyclic-AMP

A Functional Second Messenger for Assessing GPCR Target Activation

Cisbio International, France

Seite 036