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Issue 4/2007

Release date: 04/16/2007

Editorial

What is Biotechnology?

J. van Empel, A. Seidinger

page 01

Events

German-British Co-Operation in R&D

page 012

European Excellence Network Nano2Life

page 012

bioLOGIC Europe Now in its 8th Successive Year

page 013

Interview

Promoting Research

Questions to the New DFG President

Prof. Dr.-Ing. M. Kleiner, German Research Foundation

page 014

Europe

EUCOMM

The European Conditional Mouse Mutagenesis Program

W. Wurst et al., GSF Research Center for Environment and Health, Neuherberg, Germany; N. Rosenthal, EMBL Monterontondo, Italy

page 016

Stem Cells

Regeneration - Stem Cell Technology

Promises, Problems and Regulations

I. Herrmann, Stem Cell Network North Rhine-Westphalia; M. Heyer, exam. jur., Institute of Science and Ethics (IWE), Germany

page 020

Systems Biology

Why Systems Biology Is (Not) Called Systems Biology

Prof. Dr. O. Wolkenhauer, University of Rostock, Germany

page 038

Cell Biology

Mitochondrial Dysfunction:

Mechanism of Intracellular Sensing

Dr. S. Duvezin-Caubet, Dr. A.S. Reichert, University of Munich, Germany

page 041

The Obstacle Course of Drugs in the Body

Predictive Tools for the in vivo Barrier Crossing of Drugs

Prof. Dr. H. Wunderli-Allenspach, Dr. S.D. Krämer, ETH Zurich, Switzerland

page 045

Microbiology

Lactococcus lactis in the 21st Century

Meeting a Surprisingly Versatile Bacterium

I. Mierau, NIZO food research, The Netherlands

page 048

Virology

Advancing AIDS Vaccine Development

The Value of a Scientific Consortium

E. Carrow, PhD, NAC, International AIDS Vaccine Initiative

page 053

Proteomics

Yeast-based Screening Assays

Identification of Protein Interactions

Dr. D. Auerbach, Dualsystems Biotech, Switzerland

page 060

Molecular Diagnostics

Personalized Medicine

Pharmacogenomics, Theragnostics and Prognomics

R.Y. Zhao, Ph.D., M.S., et al., University of Maryland School of Medicine, USA

page 062

Data Management

Research Highlights on Bioinformatics Development over the Last Decade

G. Williams, IDBS, UK

page 068

Liquid Handling

Microfluidics in Life Sciences

Controlled Fluid Handling down to fL

Dr. N. Pamme, Dr. A. Iles, University of Hull, UK

page 070

Application Notes

HTS and Fluorescence Polarization Measurement

Mag. S. Moritz, Beckman Coulter, Austria

page 075

Picture in Picture

Overlaying Optical and Scanning Force Microscopy Images

C. Löbbe, K. Poole, JPK Instruments, Germany

page 076

Cover Story

Sleuthing the Virus …

Widefield Image Acquisition and Analysis

F. Viereck et al., Carl Zeiss Imaging Solutions, Germany

page 078