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Issue 11-12/2010

Release date: 12/08/2010

Life Science

PKA, an All-rounder in Signal Transduction

A story about structure, function an distribution

Prof. Dr. F. W. Herberg et al., University of Kassel, Germany

page 11

Synthetic Attenuated Virus Engineering (SAVE

A Novel Strategy to Generate Viral Vaccine Candidates

M. Mordechai et al., Stony Brook University, New York, USA

page 14

A Role for an Untranscribed Gene

Keeping the Distance

T. Kobayashi, The Graduate University for Advanced Studies, Japan

page 16

Pharmaceutics & Drug Discovery

Recombinant Human α1-Antitrypsin

Expression in Pichia pastoria and Nanoencapsulation

S. Arjmand et al., National Institute of Genetic, Tehran Iran

page 21

Advertorial

Microliters Matter

When Analyzing Cancer at the Molecular Level

Artel USA

page 22

Pharmaceutics & Drug Discovery

Open Innovation

Accelerate Innovation in Drug Discovery

European ScreeningPort, Hamburg, Germany

page 23

Cover Story

Complex Microscopy

Increasing Usability and Maintaining Quality

Olympus Europa, Hamburg, Germany

page 24

Application Notes

Next Generation Sequencing for All

Amplicon-Based Targeted Resequencing

Dr. R. Oehlmann, S. Kotschote IMGM Laboratories, Martinsried, Germany

page 28

Mercury and Arsenic

Speciation Analysis by IC-ICP/MS

A. Steinbach et al., Metrohm, Herisau, Switzerland

page 30

Customized Multi-tool Laboratory Robots

Automation of Manual Synthesis Procedures

B. Kusserow, HiTec Zang, Herzogenrath, Germany

page 33

Analysis of Allergens in Perfume

Comprehensive 2D GC using combined SIM/Scan qMS detection

M. Geissler, Shimadzu Europe, Duisburg, Germany, et al.

page 36

Advertorial

Temperature Distribution Matters

Verified Oven Specifications

T. Tröndle, Testo industrial services, Kirchzarten, Germany

page 38

Events

SBS 17th Annual Conference and Exhibition

page 6

Magazine

Nobel Prizes 2010

page 7

Events

Horizons In Molecular Biology

page 8

Material Sciences

Multifunctional Nanoparticles for Biomedical Applications

IMIKRID: an Integrated Microfluidic Diagnostic System

Dr. J. Probst, Fraunhofer ISC, Würzburg, Germany

page 9